Manchester United could be without six players for Thursday's Europa League semi-final second-leg clash with Athletic Bilbao at Old Trafford.
Boasting a 3-0 first-leg advantage, the Red Devils will be without Lisandro Martinez (knee), Diogo Dalot (calf), Joshua Zirkzee (thigh) and Ayden Heaven (ankle) as they all continue to recover from injury.
Ruben Amorim's side will be sweating over the fitness of Matthijs de Ligt who was forced off with a muscle problem in Sunday's 4-3 Premier League loss to Brentford; both De Ligt and Toby Collyer (leg) will be assessed ahead of kickoff.
If De Ligt is not fit to feature, then Amorim may decide to use a back three of Victor Lindelof, Harry Maguire and Leny Yoro which started the first leg. Luke Shaw and Noussair Mazraoui are also candidates to start as centre-backs.
Mazraoui has recently been operating as a right wing-back in the absence of Dalot, but if Amorim opts to use the Moroccan as a right-sided centre-back, Amad Diallo could be handed a start on the flank after making a few substitute appearances, and scoring against Brentford last time out, since returning from injury.
Patrick Dorgu began at right wing-back last weekend, but he is expected to move over to the left, while Casemiro could be recalled at the expense of Kobbie Mainoo to start in centre-midfield alongside Manuel Ugarte.
Captain Bruno Fernandes netted a brace in the first leg, taking his goal tally in the Europa League to a tournament-high seven this season, and he is set to link up with Alejandro Garnacho and Rasmus Hojlund in attack. Chido Obi-Martin, meanwhile, started against Brentford, but the 17-year-old is ineligible to play in the Europa League.
Manchester United possible starting lineup: Onana; Lindelof, Maguire, Yoro; Mazraoui, Ugarte, Casemiro, Dorgu; Fernandes, Garnacho; Hojlund
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