Real Madrid boss Carlo Ancelotti will again be without the services of a number of important players for Wednesday's La Liga contest with Athletic Bilbao at San Mames.
Rodrygo, Gareth Bale, Marco Asensio, Andriy Lunin and Marcelo remain out following positive coronavirus tests, while Luka Modric is also unavailable for selection despite the Croatian now testing negative for the virus.
That lengthy list of COVID absentees has now been added to by Isco and David Alaba, while Dani Carvajal is also sidelined due to a muscular problem and Dani Ceballos is injured too.
Casemiro's booking in Sunday's goalless draw with Cadiz has ruled him out of this match, meaning that Eduardo Camavinga could come into the XI.
Eden Hazard failed to make the most of his opportunity against Cadiz, with the Belgium international seemingly coming to the end of his time at Bernabeu.
Ancelotti could now decide to drop Hazard back to the bench, with Lucas Vazquez being pushed further forward in a front three with Karim Benzema and Vinicius Junior.
As a result, there could be a spot at right-back for Nacho, with Carvajal unlikely to be risked even if he is passed fit for Real Madrid's final match of the year.
Real Madrid possible starting lineup: Courtois; Nacho, Militao, Vallejo, Mendy; Valverde, Camavinga, Kroos; Vazquez, Benzema, Vinicius
