Manchester United manager Ralf Rangnick will be working with no fewer than six enforced absentees for Thursday's Premier League clash with Chelsea at Old Trafford.
Paul Pogba has likely played his final game for the 20-time English champions and remains on the sidelines alongside Luke Shaw and Edinson Cavani, while Mason Greenwood is still suspended by the club.
Fred's hip problem will not let up in time for Thursday's game either, while Harry Maguire (knee) and Jadon Sancho (illness) have also been ruled out. Aaron Wan-Bissaka will need assessing before the match too.
Maguire was on the bench for the Arsenal game anyway due to a bomb threat to his home, with Victor Lindelof and Raphael Varane likely pairing up at the back again.
Diogo Dalot was unlucky not to score on Saturday - hitting the crossbar and forcing Aaron Ramsdale to tip his effort onto the post - and the right-back will expect to start over the afflicted Wan-Bissaka.
Alex Telles was at fault for two of Arsenal's goals but is unlikely to lose his spot with Shaw still on the sidelines, and Nemanja Matic's place alongside Scott McTominay is not under any real risk with Fred and Pogba ruled out.
Bruno Fernandes's penalty miss capped off another underwhelming display from the Portuguese, who will still expect to hold his position over Jesse Lingard and Juan Mata.
Anthony Elanga and Marcus Rashford can also look forward to starts alongside Cristiano Ronaldo, who joined the Premier League's 100 club with his consolation effort at the Emirates Stadium.
Man United possible starting lineup: De Gea; Dalot, Varane, Lindelof, Telles; McTominay, Matic; Elanga, Fernandes, Rashford; Ronaldo
> Click here to see how Chelsea could line up for this clash
