Tottenham Hotspur head coach Ange Postecoglou will be without Micky van de Ven for Saturday's Premier League clash with London rivals Fulham at Craven Cottage.

The Dutch defender was withdrawn early in the second half of last weekend's 4-0 win over Aston Villa with a hamstring injury, albeit not as severe as the one he sustained back in November.

Tottenham are supposedly hopeful that Van de Ven's issue will clear up during the international break, but the former Wolfsburg man will be one of four definite absentees for the Lilywhites this weekend.

Ryan Sessegnon (hamstring), Fraser Forster (foot) and Manor Solomon (knee) are also in the treatment room, and there is still a question mark over the head of Richarlison (knee), but Postecoglou is confident that he can be part of the squad.

With Van de Ven out of the picture, Radu Dragusin will come in for his maiden Premier League start since his January arrival from Genoa, joining Cristian Romero, Destiny Udogie, Pedro Porro and Guglielmo Vicario in an otherwise untouched backline.

Senegalese midfielder Pape Sarr is having a back issue carefully managed, but he should still get the nod alongside Yves Bissouma in midfield, as James Maddison operates just ahead of the duo.

Fresh from scoring one of his own and setting up two more at Villa Park, Son Heung-min should be deployed in the central role if Richarlison is spared, supported by Dejan Kulusevski and Brennan Johnson out wide.

Tottenham Hotspur possible starting lineup:
Vicario; Porro, Romero, Dragusin, Udogie; Sarr, Bissouma; Kulusevski, Maddison, Johnson; Son