Barcelona will be without the services of their leading goalscorer Robert Lewandowski for Sunday's La Liga contest with Getafe at Camp Nou.
A brilliant campaign to date has seen the Poland international score 22 goals in 23 appearances in all competitions, including 13 in 15 La Liga outings.
However, the 34-year-old will serve the second of a three-game suspension in this match, while Ferran Torres is also banned due to his red card against Atletico Madrid in the league last time out.
Xavi's side were in Copa del Rey action on Thursday night, recording a 5-0 victory over Ceuta to progress to the quarter-finals of the competition.
There will be wholesale changes from that match, with Ronald Araujo and Frenkie de Jong, who were left out of the squad against Ceuta, returning to the XI.
Gavi is likely to play further forward, with Pedri featuring alongside De Jong and Sergio Busquets in a three-man midfield.
Ousmane Dembele should get the nod off the right, while it is likely that Ansu Fati will feature through the middle, with Torres banned and Memphis Depay heading for Atletico Madrid.
Araujo should be joined by Jules Kounde and Andreas Christensen at the back, while Alejandro Balde is expected to feature as the left-back for the La Liga leaders.
Barcelona possible starting lineup: Ter Stegen; Araujo, Kounde, Christensen, Balde; F de Jong, Busquets, Pedri; Dembele, Fati, Gavi
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