Facing a one-goal deficit to make up if they are to reach the quarter-finals of the Champions League, the second leg of Porto's last-16 tie against Inter Milan takes place at Estadio do Dragao on Tuesday.
Dragoes coach Sergio Conceicao will be obliged to make one major change: having seen red in Milan for being booked twice - once for dissent, the other for a foul - midfield mainstay Otavio must watch from the sidelines due to suspension.
Galeno and Andre Franco are among those hoping to deputise for the Portugal international, while Reading youth product Danny Loader provides another option for former Inter midfielder Conceicao.
After picking up a minor injury against Estoril on Friday, Canadian midfielder Stephen Eustaquio aims to be fit in time to feature, but Marko Grujic and Matheus Uribe are the hosts' most likely central pairing in any case.
Evanilson's thigh injury means he is set to miss out, while Mehdi Taremi comes back in from the start after being benched at the weekend; despite being Porto's main goal threat, the latter has found the net only twice in his 11 last appearances.
Both Pepes are expected to play as well, with the veteran defender lining up at the heart of a back four, not long after celebrating his 40th birthday. Meanwhile, the 26-year-old Brazilian winger should take a place in Taremi's supporting cast.
Porto possible starting lineup: Costa; Mario, Pepe, Cardoso, Sanusi; Grujic, Uribe; Franco, Pepe, Galeno; Taremi
> Click here to see how Inter Milan could line up for this Champions League contest
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