Union Berlin will be looking to build upon their first victory since the restart over Koln as they play host to bottom-of-the-table SC Paderborn on Tuesday.
In contrast, Paderborn are 11 points from safety and their relegation to the German second division has been all but confirmed following their 5-1 thrashing by Werder Bremen.
Match preview
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Union Berlin had not won in seven attempts in the Bundesliga before their weekend victory over Koln, but Die Eisernen have practically guaranteed their safety in the division following that 2-1 win.
Indeed, Urs Fischer's men are seven points clear of the drop zone with three rounds of matches remaining, and they will no doubt feel confident of picking up a second win on the bounce against an out-of-sorts Paderborn side.
Union dropped one place to 14th after Augsburg secured a vital victory over fellow relegation candidates Mainz on Sunday, but Fischer's side still have home fixtures against two of the Bundesliga's bottom three to look forward to as the season draws to a close.
Tuesday's clash represents a great chance for Union to record their first win on home turf since January, although Paderborn did manage to salvage a point as the sides played out a 1-1 draw back in December.
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In contrast, Paderborn are set for a swift return to the 2.Bundesliga after they suffered a humiliating 5-1 defeat against 17th-placed Werder Bremen in their own back yard.
The result more or less epitomised Paderborn's season during their return to the big time, and Steffen Baumgart's side can now only finish in the relegation playoff spot at the very most.
Two of Paderborn's four wins all season have actually come on the road - including their most recent victory against Freiburg in January - but they have only netted once in their last four away matches in the German top flight.
Paderborn never looked likely to produce a great escape and their relegation to the second division will be confirmed if they lose to Union on Tuesday.
Union Berlin Bundesliga form: LLDLDW
Paderborn Bundesliga form: DDDLDL
Team News
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Robert Andrich is back in the fold for Union having served his one-match suspension against Koln, and the 25-year-old is expected to return to the middle of the park.
However, Christopher Lenz was not involved last time out and it remains to be seen whether the German will be fit in time for the midweek clash.
Fischer may decide to start with a back three for the tie with Paderborn, meaning that Neven Subotic could play a part from the opening whistle.
As far as Paderborn are concerned, Uwe Hunemeier and Streli Mamba return from suspension and the duo will likely slot right back into the starting lineup.
Jan-Luca Rumpf made his debut in the thrashing against Werder but should be replaced by Hunemeier, while Mamba is expected to start up top as a lone striker.
Sebastian Schonlau has also been struggling with injuries recently, but it has been suggested that the German may recover in time to be involved here.
Union Berlin possible starting lineup:
Gikiewicz; Friedrich, Schlotterbeck, Subotic; Trimmel, Andrich, Gentner, Bulter; Ingvartsen, Malli; Andersson
Paderborn possible starting lineup:
Zingerle; Drager, Hunemeier, Strohdiek, Collins; Vasiliadis, Schonlau; Proger, Srbeny, Antwi-Adjei; Mamba
We say: Union Berlin 2-1 Paderborn
Union have not exactly hit the ground running since the restart, but that victory over Koln will have done wonders for their confidence. Paderborn's story could not be more different, though, and we expect the home side to take the spoils and seal Paderborn's fate on Tuesday.
