Liverpool manager Jurgen Klopp has dropped Loris Karius in favour of Simon Mignolet for the trip to Middlesbrough.
Ragnar Klavan steps into the heart of the Reds' backline after Joel Matip was left out of the squad. Dejan Lovren, who was a fitness doubt in the build-up to the game, starts alongside the Estonian.
Divock Origi starts up for the visitors and will make his 50th senior Liverpool appearance.
Meanwhile, George Friend has returned to training with Boro, but is not risked by manager Aitor Karanka.
Gaston Ramirez is still out with a foot injury, but Alvaro Negredo starts after recovering from a hamstring injury.
Middlesbrough: Valdes, Barragan, Chambers, Gibson, Fabio, Clayton, De Roon, Forshaw, Traore, Fischer, Negredo
Subs: Guzan, Nsue, Bernardo, Leadbitter, Downing, Rhodes, Nugent
Liverpool: Mignolet, Clyne, Lovren, Klavan, Milner, Henderson, Wijnaldum, Lallana, Firmino, Mane, Origi
Subs: Karius, Moreno, Lucas, Stewart, Alexander, Woodburn, Ejaria
