| | First Half starts. |
| 3' | | Offside - Sampdoria. Mikkel Damsgaard with a pass, however Francesco Caputo is in offside. |
| 4' | | Corner - Napoli. Conceded by Tommaso Augello. |
| 7' | | New attacking attempt. Victor Osimhen - Napoli - shot with right foot from outside the box is saved in the right corner. Assist - Lorenzo Insigne. |
| 10' | | Goal! Sampdoria 0, Napoli 1. Victor Osimhen - Napoli - shot with right foot from few metres to the right corner. Assist - Lorenzo Insigne. |
| 13' | | Shot blocked. Antonio Candreva - Sampdoria - shot with left foot from the right side of the box is blocked. |
| 13' | | Corner - Sampdoria. Conceded by Kalidou Koulibaly. |
| 15' | | Corner - Napoli. Conceded by Emil Audero. |
| 16' | | Shot blocked. Piotr Zielinski - Napoli - shot with right foot from outside the box is blocked. Assist - Lorenzo Insigne. |
| 17' | | Missed chance. Hirving Lozano - Napoli - shot with right foot from the right side of the box is high and wide to the left. Assist - Victor Osimhen. |
| 19' | | Shot blocked. Bartosz Bereszynski - Sampdoria - shot with right foot from the centre of the box is blocked. Assist - Francesco Caputo. |
| 19' | | New attacking attempt. Adrien Silva - Sampdoria - shot with right foot from outside the box is saved in the top right corner. Assist - Bartosz Bereszynski. |
| 19' | | Corner - Sampdoria. Conceded by David Ospina. |
| 19' | | New attacking attempt. Maya Yoshida - Sampdoria - shot with the head from the centre of the box is saved in the left corner. Assist - Antonio Candreva with a cross. |
| 21' | | Offside - Napoli. André-Frank Zambo Anguissa with a pass, however Victor Osimhen is in offside. |
| 21' | | New attacking attempt. Antonio Candreva - Sampdoria - shot with right foot from the right side of the box is saved by goalkeeper in the centre of the goal. Assist - Francesco Caputo. |
| 22' | | Amir Rrahmani - Napoli - won a free kick in defence. |
| 22' | | Fouled by Francesco Caputo - Sampdoria |
| 23' | | Fouled by Fabián Ruiz - Napoli |
| 23' | | Morten Thorsby - Sampdoria - won a free kick on the right wing. |
| 25' | | Shot blocked. Mikkel Damsgaard - Sampdoria - shot with right foot from outside the box is blocked. Assist - Bartosz Bereszynski. |
| 27' | | Fouled by Omar Colley - Sampdoria |
| 27' | | Victor Osimhen - Napoli - won a free kick in defence. |
| 28' | | Fouled by Mikkel Damsgaard - Sampdoria |
| 28' | | Hirving Lozano - Napoli - won a free kick on the right wing. |
| 28' | | Mikkel Damsgaard - Sampdoria - receive yellow card for a foul. |
| 31' | | Shot blocked. Hirving Lozano - Napoli - shot with left foot from outside the box is blocked. Assist - Giovanni Di Lorenzo. |
| 31' | | Corner - Napoli. Conceded by Omar Colley. |
| 35' | | Fouled by Fabián Ruiz - Napoli |
| 35' | | Francesco Caputo - Sampdoria - won a free kick on the left wing. |
| 35' | | Missed chance. Antonio Candreva - Sampdoria - shot with right foot from outside the box goes high. |
| 38' | | New attacking attempt. Lorenzo Insigne - Napoli - shot with right foot from outside the box is saved in the right corner. Assist - Piotr Zielinski. |
| 39' | | Goal! Sampdoria 0, Napoli 2. Fabián Ruiz - Napoli - shot with left foot from outside the box to the left corner. Assist - Lorenzo Insigne. |
| 42' | | New attacking attempt. Francesco Caputo - Sampdoria - shot with right foot from the centre of the box is saved by goalkeeper in the centre of the goal. Assist - Antonio Candreva with a cross. |
| 42' | | Corner - Sampdoria. Conceded by Kalidou Koulibaly. |
| 45' | | Corner - Sampdoria. Conceded by Kalidou Koulibaly. |
| 45+1' | | Adrien Silva - Sampdoria - won a free kick on the left wing. |
| 45+1' | | Fouled by Victor Osimhen - Napoli |
| 45+1' | | First Half ended - Sampdoria 0, Napoli 2. |
| 45' | | Second Half starts Sampdoria 0, Napoli 2. |
| 46' | | Hand ball by André-Frank Zambo Anguissa - Napoli |
| 48' | | Substitution - Napoli. Kostas Manolas for Amir Rrahmani - injury. |
| 50' | | Shot blocked. Fabio Quagliarella - Sampdoria - shot with right foot from outside the box is blocked. Assist - Adrien Silva. |
| 50' | | Goal! Sampdoria 0, Napoli 3. Victor Osimhen - Napoli - shot with right foot from the centre of the box to the left corner. Assist - Hirving Lozano with a cross. |
| 54' | | André-Frank Zambo Anguissa - Napoli - won a free kick in attack. |
| 54' | | Fouled by Morten Thorsby - Sampdoria |
| 55' | | Substitution - Sampdoria. Ernesto Torregrossa for Fabio Quagliarella. |
| 55' | | Substitution - Sampdoria. Albin Ekdal for Adrien Silva. |
| 56' | | New attacking attempt. Piotr Zielinski - Napoli - shot with left foot from outside the box is saved by goalkeeper in the centre of the goal. Assist - Hirving Lozano. |
| 57' | | Missed chance. Morten Thorsby - Sampdoria - shot with left foot from outside the box missed to the left. |
| 58' | | Missed chance. Lorenzo Insigne - Napoli - shot with right foot from the left side of the box is close, but misses the top right corner. Assist - Mário Rui. |
| 58' | | Hand ball by Ernesto Torregrossa - Sampdoria |
| 59' | | Goal! Sampdoria 0, Napoli 4. Piotr Zielinski - Napoli - shot with left foot from the centre of the box to the right corner. Assist - Hirving Lozano. |
| 62' | | Fouled by Kalidou Koulibaly - Napoli |
| 62' | | Omar Colley - Sampdoria - won a free kick in defence. |
| 63' | | Missed chance. Antonio Candreva - Sampdoria - shot with left foot from outside the box is very close to the goal. Assist - Ernesto Torregrossa. |
| 64' | | Fouled by Omar Colley - Sampdoria |
| 64' | | Piotr Zielinski - Napoli - won a free kick in defence. |
| 64' | | Missed chance. Victor Osimhen - Napoli - shot with right foot from the left side of the box missed. Assist - Lorenzo Insigne with a through ball. |
| 68' | | Substitution - Napoli. Matteo Politano for Lorenzo Insigne. |
| 68' | | Substitution - Napoli. Eljif Elmas for Piotr Zielinski. |
| 71' | | Substitution - Sampdoria. Fabio Depaoli for Bartosz Bereszynski. |
| 71' | | Substitution - Sampdoria. Kristoffer Askildsen for Morten Thorsby. |
| 72' | | Corner - Sampdoria. Conceded by Kalidou Koulibaly. |
| 73' | | Offside - Sampdoria. Antonio Candreva with a pass, however Francesco Caputo is in offside. |
| 74' | | New attacking attempt. Antonio Candreva - Sampdoria - shot with right foot from outside the box is saved in the right corner. Assist - Albin Ekdal. |
| 75' | | Fouled by Fabio Depaoli - Sampdoria |
| 75' | | Mário Rui - Napoli - won a free kick on the left wing. |
| 76' | | André-Frank Zambo Anguissa - Napoli - won a free kick in attack. |
| 76' | | Fouled by Fabio Depaoli - Sampdoria |
| 76' | | Fabio Depaoli - Sampdoria - receive yellow card for a foul. |
| 77' | | New attacking attempt. Hirving Lozano - Napoli - shot with right foot from outside the box is saved by goalkeeper in the centre of the goal. Assist - Mário Rui. |
| 78' | | Fouled by Kostas Manolas - Napoli |
| 78' | | Francesco Caputo - Sampdoria - won a free kick in attack. |
| 79' | | Shot blocked. Antonio Candreva - Sampdoria - shot with right foot from outside the box is blocked. |
| 81' | | Shot blocked. Hirving Lozano - Napoli - shot with right foot from the left side of the box is blocked. Assist - Matteo Politano. |
| 81' | | Corner - Napoli. Conceded by Fabio Depaoli. |
| 81' | | Substitution - Napoli. Andrea Petagna for Hirving Lozano. |
| 82' | | Substitution - Napoli. Adam Ounas for Victor Osimhen. |
| 83' | | Corner - Napoli. Conceded by Tommaso Augello. |
| 84' | | Fouled by Fabio Depaoli - Sampdoria |
| 84' | | Mário Rui - Napoli - won a free kick in defence. |
| 84' | | Substitution - Sampdoria. Riccardo Ciervo for Francesco Caputo. |
| 85' | | New attacking attempt. Adam Ounas - Napoli - shot with left foot from the centre of the box is saved in the right corner. Assist - Andrea Petagna with a head. |
| 85' | | Missed chance. André-Frank Zambo Anguissa - Napoli - shot with left foot from outside the box is high and wide to the left. |
| 86' | | Fabián Ruiz - Napoli - won a free kick in defence. |
| 86' | | Fouled by Ernesto Torregrossa - Sampdoria |
| 87' | | Fouled by Kostas Manolas - Napoli |
| 87' | | Mikkel Damsgaard - Sampdoria - won a free kick in defence. |
| 87' | | Kostas Manolas - Napoli - receive yellow card for a foul. |
| 89' | | Shot blocked. Fabián Ruiz - Napoli - shot with left foot from outside the box is blocked. Assist - Giovanni Di Lorenzo. |
| 90+1' | | Second Half ended - Sampdoria 0, Napoli 4. |
| | Thats all. Game finished - Sampdoria 0, Napoli 4. |