Liverpool could reportedly be without Mohamed Salah, Jordan Henderson, Joe Gomez and Andrew Robertson for the club's meeting with Crystal Palace in the Premier League later this month.
Salah has nursed an ankle injury for a few weeks and aggravated the problem during Liverpool's 3-1 win over Manchester City.
Robertson has also pulled out of internationals this month after revealing that an ankle injury had prevented him from training for two weeks prior to the game against Pep Guardiola's side.
According to The Mirror, injuries to Henderson and Gomez mean that Liverpool are now sweating on the fitness of four key players ahead of the meeting at Selhurst Park.
Henderson has pulled out of England's game with Kosovo due to a virus, while Gomez was sidelined by a challenge from Kieran Trippier.
Joel Matip and Xherdan Shaqiri are Jurgen Klopp's other two main injury concerns, with neither expected to return until the end of the month.
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