Bayer Leverkusen gave all they had but were unable to pick up the win they required to progress in a 1-1 draw against Barcelona.
The hosts needed a victory to advance through Group E, but countless chances passed them by in a one-sided second half at the BayArena.
Javier Hernandez had earlier cancelled out Lionel Messi's opener in the opening quarter of the match, which proved to be the only goals of the evening.
Relive the 90 minutes of action with Sports Mole's live text coverage below.
BAYER LEVERKUSEN XI: Leno, Tah, Hilbert, Wendell, Omer, Hakan, Kramer, Bellarabi, Kampl, Mehmedi, Hernandez
BARCELONA XI: Ter Stegen, Bartra, Alba, Adriano, Vermaelen, Rakitic, Samper, Kaptoum, Messi, Munir, Sandro
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BAYER LEVERKUSEN SUBS: Kresic, Ramalho, Papadopoulos, Boenisch, Donati, Brandt, Kiessling
BARCELONA SUBS: Bravo, Masip, Mascherano, Busquets, Camara, Gumbau, Suarez
© Getty Images
Roger Schmidt: "Barcelona are in great shape. With Messi being fit again, they are even stronger - he is the best player in the world after all. There is no way to completely deny him. Together with Bayern Munich, they are probably the best side in the world. It is going to be tough. It doesn't matter [that Barcelona are already through] Barca always want to win and I expect them to field their best players."
Luis Enrique: "I have to take into account all the situations. There are players who I have rested, some have stayed [in Barcelona]. We can take some players from the youth side, and from there play with what we have. I take into account the games they have played, the minutes, whether they have been injured, or if they have made transatlantic voyages."
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Javier Hernandez has scored 12 goals in his last 11 games in all competitions for Leverkusen. Can't stop scoring! pic.twitter.com/YfsKvQ38Qn
— Squawka Football (@Squawka) December 9, 2015
BAYER LEVERKUSEN SUBS: Kresic, Ramalho, Papadopoulos, Boenisch, Donati, Brandt, Kiessling
BARCELONA SUBS: Bravo, Masip, Mascherano, Busquets, Camara, Gumbau, Suarez
© Getty Images
© Getty Images