Napoli must pick themselves up from a damaging defeat at the hands of Serie A title rivals Juventus at the weekend when Liverpool visit the Stadio San Paolo on Wednesday night.
Last season's Champions League runners-up top Group C after matchday one, when Napoli only managed a goalless draw with Red Star Belgrade.
In manager Carlo Ancelotti they have one of the most experienced Champions League coaches around, though, with the Italian having lifted the trophy a record-equalling three times and led eight clubs in the competition.
Here, Sports Mole looks at how Napoli could line up for the visit of Jurgen Klopp's Premier League title hopefuls.
Out: Alex Meret (arm), Faouzi Ghoulam (knee), Amin Younes (Achilles), Vlad Chiriches (knee)
Doubtful: None
Predicting an Ancelotti team has not been easy since his arrival at the Stadio San Paolo, with the Italian having used four different formations in his eight matches at the helm so far.
The recent preference has been a 4-4-2 system, though, and despite it not working against Juventus at the weekend, he could look to stick with that for this match against Liverpool.
The biggest decision comes up front, where Ancelotti must decide whether to partner Dries Mertens or Arkadiusz Milik with the in-form Lorenzo Insigne.
Rumoured Liverpool transfer target Piotr Zielinski should continue on the left flank with Jose Callejon on the opposite wing if Ancelotti sticks with the 4-4-2 formation.
Alex Meret, Faouzi Ghoulam, Amin Younes and Vlad Chiriches are all long-term absentees, but Ancelotti has no new injury concerns following the weekend defeat to Juve.
> Click here to see how Liverpool could line up for this fixture
